Calocurb is 100% plant based and contains no fillers, stimulants or synthetic properties. It’s also GMO-free, gluten free and GRAS Generally Recognized as Safe approved. In fact, Calocurb only has four ingredients Sourced from a specific variety of hops flower grown in clean, green New Zealand, it activates the ‘stop-eating signal’. Amarasate Am-ar-eh-sate works by stimulating tastebuds in the gut to release hormones which send a natural fullness signal to the brain to help manage appetite